Unexplained loss of muscle mass, also known as idiopathic sarcopenia, is a concerning condition characterized by progressive and involuntary loss of skeletal muscle that cannot be attributed to a specific disease or health condition.
Potential causes that must first be ruled out include:
If muscle loss persists after excluding these factors, further medical evaluation is warranted because idiopathic sarcopenia can severely impact strength and mobility.
Common signs and symptoms include:
To diagnose idiopathic sarcopenia, physicians will conduct a medical history and physical exam, looking for less muscle bulk and strength compared to the patient’s prior baseline. They may order lab tests to evaluate hormones, inflammatory markers or nutrients/minerals.
Diagnostic imaging like an MRI or CT scan can help exclude muscle disorders or nerve damage. Often, a biopsy of the affected muscle is done to examine muscle fibers and cellular changes indicative of sarcopenia.
Treatment focuses on slowing further muscle loss. Approaches may include:
Research continues into fully understanding what triggers unexplained muscle wasting in hopes of discovering a cure. Anyone experiencing concerning unintentional muscle loss should see their doctor for proper medical evaluation, especially older adults over 50 years old. The compassionate medical team at Hormone Wellness Institute is also here to help evaluate potential hormonal causes underlying stubborn muscle loss issues.